KMID : 0383820160790030153
|
|
Tuberculosis and Respiratory Diseases 2016 Volume.79 No. 3 p.153 ~ p.157
|
|
Association of Serum Vitamin D Levels with Bacterial Load in Pulmonary Tuberculosis Patients
|
|
B. Yuvaraj
M. G. Sridhar S. Vinod Kumar T. Kadhiravan
|
|
Abstract
|
|
|
Background : Vitamin D is known to have diverse effects on various systems in the body. There is evidence to suggest that a link exists between the serum vitamin D status and tuberculosis. The present study was designed to assess the alterations in serum 25-hydroxyvitamin D levels in newly diagnosed sputum acid fast bacilli (AFB) positive pulmonary tuberculosis patients and to study the association, if any, between serum vitamin D levels and different levels of sputum smear positivity.
Methods : Serum 25-hydroxyvitamin D levels were estimated in 65 sputum AFB positive pulmonary tuberculosis patients and 65 age and gender-matched healthy controls.
Results : The levels of serum 25 hydroxy-vitamin D in tuberculosis patients were not statistically different from the levels of serum 25 hydroxy-vitamin D in healthy controls. However, among patients with pulmonary tuberculosis, there was a significant negative correlation between the levels of serum 25 hydroxy-vitamin D and levels of sputum positivity.
Conclusion : Serum vitamin D levels negatively correlates with bacterial load in patients with active pulmonary tuberculosis.
|
|
KEYWORD
|
|
Vitamin D, Tuberculosis, Pulmonary
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|